Related Experiment Video
Updated: Aug 6, 2026

10:11
The Benthic Exchange of O2, N2 and Dissolved Nutrients Using Small Core Incubations
Published on: August 3, 2016
The Great American Biotic Interchange
1Department of Anatomy, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Current Biology : CB
|July 20, 2026
Summary
The Isthmus of Panama's emergence 5 million years ago enabled a two-way exchange of large land mammals. This event significantly impacted animal migration and biodiversity across the Americas.
Area of Science:
- Paleontology
- Zoology
- Geology
Background:
- The formation of the Isthmus of Panama approximately five million years ago was a pivotal geological event.
- This land bridge connected North and South America, facilitating faunal interchange.
Purpose of the Study:
- To introduce the concept of the Great American Biotic Interchange.
- To highlight the two-way exchange of large land animals following the isthmus's emergence.
Main Methods:
- Review of paleontological and geological evidence.
- Analysis of fossil records detailing faunal distribution.
Main Results:
- Documented the significant migration of large land mammals between the two continents.
- Identified distinct North American and South American fauna that crossed the isthmus.
Conclusions:
- The emergence of the Isthmus of Panama triggered a major event in evolutionary history.
- This interchange profoundly shaped the mammalian ecosystems of North and South America.
Related Concept Videos
Symbiosis
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
Gene Flow
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
Keystone Species
Measures of species biodiversity, such as richness (i.e., the number of species present) and evenness (i.e., their relative abundance), describe an ecological community’s structure. Many factors affect community structure, including abiotic factors (e.g., sunlight and nutrients), disturbances (e.g., fire or flood), species interactions (e.g., predation or competition), and chance events (e.g., foreign species invasion). Certain species—such as keystone species—also play a pivotal role in the...
Threats to Biodiversity
There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
Migration
Migration is long-range, seasonal movement from one region or habitat to another. This common strategy, carried out by many different organisms around the world, is an adaptive response that typically corresponds to changes in an organism’s environment, like resource availability or climate. Migrations can involve huge groups of thousands of animals as well as single individuals traveling alone and can range from thousands of kilometers to just a few hundred meters.
What are Biogeochemical Cycles?
The most common elements in organic molecules, carbon, hydrogen, oxygen, nitrogen, sulfur, and phosphorus, are only available in the ecosystem in limited amounts. Therefore, these nutrients must be recycled through both biotic and abiotic components of the ecosystem, in processes generally called biogeochemical cycles.

