Infective endocarditis masquerading as a cardiac tumour in a preterm neonate

Cardiac masses in neonates are rare and most often benign tumours such as rhabdomyomas, fibromas or teratomas. Rarely, infectious lesions like infective endocarditis can present as intracardiac masses which can be considered as differential diagnosis of cardiac tumours especially in preterm neonates with prior invasive procedures or prolonged neonatal intensive care unit stay. Intracardiac masses mimic tumours on imaging leading to diagnostic challenges but histopathology remains the gold standard which was proved in our case. We present a case of a preterm neonate who was operated on for posterior urethral valve and later developed an intracardiac mass which was excised later. Early echocardiography screening and histopathological confirmation are essential for timely diagnosis and management of cardiac masses.