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Updated: Aug 6, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
09:27

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Published on: February 17, 2017

Amino acid-functionalised trehalose for multifunctional cryopreservation

Michael J Foster1, Saffron J Bryant2, Amr Taher3

  • 1School of Science and Technology, University of New England, Armidale, New South Wales, 2351, Australia. brendan.wilkinson@une.edu.au.

Journal of Materials Chemistry. B
|July 21, 2026
PubMed
Summary

No abstract available in PubMed .

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...

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