Eosinophilic gastroenteritis due to egg allergy in a 70-year-old patient

Eosinophilic gastrointestinal disorders (EGIDs) comprise a group of rare diseases characterized by eosinophilic infiltration of the gastrointestinal tract exceeding that observed under physiological conditions. Non-esophageal EGIDs are uncommon, with an estimated prevalence of 1-20 cases per 100,000 individuals, and the majority of reported cases occur in adolescent males. We describe a rare case of eosinophilic gastroenteritis most likely associated with egg allergy in a 70-year-old patient. Implementation of an egg-elimination diet resulted in complete clinical remission and marked improvement in laboratory parameters, including peripheral eosinophil counts and total as well as egg-specific IgE levels. Significant reductions were also observed in IgE sensitization to egg white, egg yolk, and major egg allergens, including ovalbumin and ovomucoid. To our knowledge, only a few cases of eosinophilic gastroenteritis have been reported in elderly patients, and no cases associated with food allergy in this age group have been identified in the published literature.