Corticosteroid therapy following infliximab rescue in acute severe ulcerative colitis: should they be continued?

In patients with acute severe ulcerative colitis (ASUC) who have received infliximab rescue therapy, the need for and timing of further steroid therapy is unclear. This brief communication explores contemporary clinical practice across Australia regarding corticosteroid management following rescue therapy in ASUC. By describing variability in real-world practice patterns and potential risks and benefits of different approaches, this article highlights current evidence gaps and the need for further studies to better inform clinical practice.