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Published on: August 8, 2025
Percutaneous Transaxillary Access for Large-Bore Cardiovascular Interventions: Evidence, Technique, and Complication
Gioel Gabrio Secco1,2, Marco Lombardi1, Edoardo Elia1
1Interventional Cardiology Unit, AOU SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Percutaneous transaxillary access offers an alternative for large-bore arterial access in structural heart interventions and mechanical circulatory support (MCS). This review details its technical aspects, challenges, and closure strategies for improved safety and reproducibility.
Area of Science:
- Cardiovascular Interventions
- Vascular Access Techniques
- Interventional Cardiology
Background:
- Percutaneous transaxillary access is an alternative to transfemoral access for large-bore arterial procedures.
- It is particularly useful for patients with challenging iliofemoral anatomy.
- The axillary/subclavian approach presents unique technical and anatomical considerations.
Purpose of the Study:
- To provide a practical framework for percutaneous transaxillary access.
- To summarize clinical evidence, technical aspects, and complication management.
- To offer procedural tips for enhancing safety and reproducibility.
Main Methods:
- Review of contemporary clinical evidence and procedural techniques.
- Emphasis on pre-procedural imaging and patient selection.
- Guidance on ultrasound/angiographic puncture and closure strategies.
Main Results:
- Transaxillary access overcomes iliofemoral limitations and allows patient mobilization during mechanical circulatory support (MCS).
- Meticulous planning, precise guidance, and appropriate closure are crucial.
- Familiarity with suture-based and balloon-assisted closure is important.
Conclusions:
- Percutaneous transaxillary access is a viable option when transfemoral access is difficult.
- Careful technique and closure management are key to success.
- This review aims to standardize and improve the safety of the procedure.
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