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Updated: Aug 6, 2026
Investigation of Protein Recruitment to DNA Lesions Using 405 Nm Laser Micro-irradiation
Published on: March 20, 2018
RI-augmented TdT-CRISPR fluorescent biosensor for sensitive quantification of DNA breakage in CT-irradiated human
Lili Ma1, Jian Zhao2, Yong Chen3
1Reproductive Center, General Hospital of Ningxia Medical University, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan, 750004, China. d202081630@alumni.hust.edu.cn.
Abstract:
Featuring a linear range of 0.001-0.4 nM and a limit of detection of 0.12 pM, the RI-enhanced TdT-CRISPR sensor precisely detects radiation-induced trace DNA damage in sperm, outperforming the conventional DFI method.
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