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Persistent Urinary Incontinence in Female Patients with Chronic Cough: A 6-month Longitudinal Analysis
Hwa Young Lee1, Seung-Eun Lee2, Noeul Kang3
1Division of Allergy, Department of Internal Medicine,, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Korea. lehwyo@catholic.ac.kr.
Urinary incontinence (UI) often persists in women with chronic cough, even after treatment. Older age, higher BMI, and less improvement in cough symptoms are linked to persistent UI.
Area of Science:
- Pulmonology
- Urology
- Clinical Medicine
Background:
- Urinary incontinence (UI) is a common comorbidity in female patients experiencing chronic cough.
- Factors influencing persistent UI and its clinical impact in this population require further elucidation.
Purpose of the Study:
- To investigate the prevalence and factors associated with persistent UI in female patients with chronic cough.
- To analyze patient-reported outcomes (PROs) related to UI and cough management over a 6-month period.
Main Methods:
- Longitudinal analysis of data from the Korean Chronic Cough Registry, including 206 female patients.
- UI status (persistent, resolved, absent) assessed at baseline and 6 months.
- Regression analyses to identify predictors of persistent UI and changes in PROs.
Main Results:
- Approximately 24.3% of patients had persistent UI at 6 months.
- Persistent UI was associated with older age (≥60 years) and higher BMI (≥25 kg/m²).
- Patients with persistent UI showed less improvement in cough hypersensitivity scores compared to those with resolved UI.
Conclusions:
- Persistent UI affects a significant portion of female chronic cough patients despite guideline-based management.
- Older age, higher BMI, and reduced improvement in cough hypersensitivity are key factors associated with persistent UI.
- Clinical attention is warranted for patients with persistent UI to address heterogeneity in treatment outcomes.
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