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Defining a Clinically Meaningful Cut Point for the Hypoglycemia Fear Survey-Parents of Young Children
Susana R Patton1, Nicole Kahhan2, Holly K O'Donnell3
1Center for Healthcare Delivery Science, Nemours Children's Health, Jacksonville, Florida, United States.
Insights
A new cut-point of 61 on the Hypoglycemia Fear Survey-Parents of Young Children (HFS-PYC) effectively identifies parents experiencing significant fear of hypoglycemia (FH). This score correlates with increased parental anxiety, diabetes distress, and higher child glucose levels.
Area of Science:
- Pediatric Endocrinology
- Psychology
- Diabetes Management
Background:
- Parental fear of hypoglycemia (FH) is common in young children with type 1 diabetes (T1D) and linked to elevated child glucose levels.
- The Hypoglycemia Fear Survey-Parents of Young Children (HFS-PYC) is a validated tool for assessing parental FH but lacks a clinical cut-point.
- Identifying a clinically meaningful cut-point for the HFS-PYC is crucial for targeted interventions and research.
Purpose of the Study:
- To establish a preliminary, clinically interpretable cut-point for the HFS-PYC.
- To determine if this cut-point associates with increased parental anxiety, diabetes distress, and specific child glycemic metrics.
- To evaluate the diagnostic accuracy of potential cut-points.
Main Methods:
- 180 parents of children with T1D completed the HFS-PYC, PROMIS-Anxiety (PROMIS-A), and Problem Areas in Diabetes Parent-Revised (PAID-PR).
- Candidate cut-points were derived using modal score distribution, mean + one standard deviation, and an elevated-item rule.
- Groups were compared based on HFS-PYC scores relative to cut-points for anxiety, distress, and child glycemic control, with diagnostic accuracy calculated against a reference standard.
Main Results:
- Candidate cut-points included ≥61 (Mode) and ≥77 (SD).
- The Mode cut-point (≥61) demonstrated the highest diagnostic accuracy (sensitivity=0.77, specificity=0.57) and differentiated parents on anxiety, distress, and some glycemic metrics.
- A score of ≥61 on the HFS-PYC identified parents with significantly higher anxiety and diabetes distress compared to those below the cut-point.
Conclusions:
- A preliminary HFS-PYC total score of ≥61 is proposed as a clinically useful cut-point.
- This cut-point effectively identifies parents experiencing heightened anxiety and diabetes distress, and children with elevated glycemic metrics.
- The ≥61 cut-point offers a practical tool for clinical screening and future research in parental fear of hypoglycemia in T1D.
Objective:
Parents of young children with type 1 diabetes (T1D) frequently experience fear of hypoglycemia (FH), which contributes to higher child glucose levels. The Hypoglycemia Fear Survey-Parents of Young Children (HFS-PYC) is a validated questionnaire used to assess parental FH, yet it lacks a clinically interpretable cut point. We sought to identify a preliminary HFS-PYC cut point that associates with higher parental anxiety, greater diabetes distress, and child glucose metrics.
Methods:
Parents (n=180) completed the HFS-PYC, PROMIS-Anxiety Short Form (PROMIS-A), and Problem Areas in Diabetes-Parent Revised (PAID-PR). We derived candidate cut points using 1) modal score distribution (mode), 2) mean plus 1 standard deviation (SD), and 3) an elevated-item rule (EI). We compared groups above vs below each cut point on PROMIS-A, PAID-PR, and child glycemic metrics. We calculated indices of diagnostic accuracy using PROMIS-A T-scores ≥60 as a reference.
Results:
Candidate cut points were ≥61 (mode) and ≥77 (SD); EI required ≥5 of 9 items rated "often/almost always." The prevalence of elevated FH ranged from 52% (mode) to 18% (SD). All cut points distinguished between parents with high vs low PROMIS-A and PAID-PR scores (p<0.001). Only the mode cut point differentiated among parents for some child glycemic metrics. The mode cut point also had the most favourable diagnostic accuracy (sensitivity=0.77, specificity=0.57) among the candidate cut points.
Conclusions:
An HFS-PYC total score ≥61 identifies parents with greater anxiety and diabetes distress and children with higher glycemic metrics and demonstrates the best diagnostic performance among candidate cut points. Pending further validation, this preliminary cut point may offer a practical starting point for clinical screening and research.
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