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Defining a Clinically Meaningful Cut-Point for the Hypoglycemia Fear Survey-Parents of Young Children
Susana R Patton1, Nicole Kahhan2, Holly K O'Donnell3
1Center for Healthcare Delivery Science, Nemours Children's Health, 807 Children's Way, Jacksonville, FL, 32207, USA.
Insights
A new cut-point of 61 on the Hypoglycemia Fear Survey-Parents of Young Children (HFS-PYC) effectively identifies parents experiencing significant fear of hypoglycemia (FH). This score correlates with increased parental anxiety, diabetes distress, and higher child glucose levels.
Area of Science:
- Pediatric Endocrinology
- Psychology
- Diabetes Management
Background:
- Parental fear of hypoglycemia (FH) is common in young children with type 1 diabetes (T1D) and linked to elevated child glucose levels.
- The Hypoglycemia Fear Survey-Parents of Young Children (HFS-PYC) is a validated tool for assessing parental FH but lacks a clinical cut-point.
- Identifying a clinically meaningful cut-point for the HFS-PYC is crucial for targeted interventions and research.
Purpose of the Study:
- To establish a preliminary, clinically interpretable cut-point for the HFS-PYC.
- To determine if this cut-point associates with increased parental anxiety, diabetes distress, and specific child glycemic metrics.
- To evaluate the diagnostic accuracy of potential cut-points.
Main Methods:
- 180 parents of children with T1D completed the HFS-PYC, PROMIS-Anxiety (PROMIS-A), and Problem Areas in Diabetes Parent-Revised (PAID-PR).
- Candidate cut-points were derived using modal score distribution, mean + one standard deviation, and an elevated-item rule.
- Groups were compared based on HFS-PYC scores relative to cut-points for anxiety, distress, and child glycemic control, with diagnostic accuracy calculated against a reference standard.
Main Results:
- Candidate cut-points included ≥61 (Mode) and ≥77 (SD).
- The Mode cut-point (≥61) demonstrated the highest diagnostic accuracy (sensitivity=0.77, specificity=0.57) and differentiated parents on anxiety, distress, and some glycemic metrics.
- A score of ≥61 on the HFS-PYC identified parents with significantly higher anxiety and diabetes distress compared to those below the cut-point.
Conclusions:
- A preliminary HFS-PYC total score of ≥61 is proposed as a clinically useful cut-point.
- This cut-point effectively identifies parents experiencing heightened anxiety and diabetes distress, and children with elevated glycemic metrics.
- The ≥61 cut-point offers a practical tool for clinical screening and future research in parental fear of hypoglycemia in T1D.
Introduction:
Parents of young children with type 1 diabetes (T1D) frequently experience fear of hypoglycemia (FH) which contributes to higher child glucose. The Hypoglycemia Fear Survey-Parents of Young Children (HFS-PYC) is a validated questionnaire to assess parental FH, yet it lacks a clinically interpretable cut-point. We sought to identify a preliminary HFS-PYC cut-point that associates with higher parent anxiety, greater diabetes distress, and child glucose metrics.
Methods:
Parents (n=180) completed the HFS-PYC, PROMIS-Anxiety (PROMIS-A) and Problem Areas in Diabetes Parent-Revised (PAID-PR). We derived candidate cut-points using (a) modal score distribution (Mode), (b) mean + one standard deviation (SD), and (c) an elevated-item rule (EI). We compared groups above versus below each cut-point on PROMIS-A, PAID-PR, and child glycemic metrics. We calculated indices of diagnostic accuracy using PROMIS-A T-scores ≥60 as a reference.
Results:
Candidate cut-points were ≥61 (Mode) and ≥77 (SD); EI required ≥5 of 9 items rated "Often/Almost Always." Prevalence of elevated FH ranged from 52% (Mode) to 18% (SD). All cut-points distinguished between parents with high versus low PROMIS-A and PAID-PR scores (p<0.001). Only the Mode cut-point differentiated among parents for some child glycemic metrics. The Mode cut-point also had the most favorable diagnostic accuracy (sensitivity=0.77, specificity=0.57) among the candidate cut-points.
Conclusions:
An HFS-PYC total score ≥61 identifies parents with greater anxiety and diabetes distress and children with higher glycemic metrics and shows the best diagnostic performance among candidate cut-points. Pending further validation, this preliminary cut-point may offer a practical starting point for clinical screening and research.
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