Related Experiment Video
Updated: Aug 6, 2026
12:10
Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
Sexual Function and Clinical Outcomes Following Rezūm Therapy for Benign Prostatic Hyperplasia: An Updated Systematic
Ivan Maulana Fakh1, Harrina Erlianti Rahardjo1
1Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Lower Urinary Tract Symptoms
|July 21, 2026
Summary
Rezūm water vapor thermal therapy (WVTT) for benign prostatic hyperplasia (BPH) preserves sexual function and relieves urinary symptoms, even in large prostates. However, evidence quality is limited, requiring cautious interpretation.
Area of Science:
- Urology
- Men's Health
- Minimally Invasive Surgery
Background:
- Benign prostatic hyperplasia (BPH) affects a significant number of men, leading to lower urinary tract symptoms (LUTS).
- Traditional BPH treatments can impact sexual function, necessitating alternative therapies.
- Rezūm water vapor thermal therapy (WVTT) offers a minimally invasive option for BPH management.
Purpose of the Study:
- To evaluate the efficacy of Rezūm WVTT on sexual function and clinical outcomes in BPH patients.
- To specifically assess outcomes in patients with large prostate volumes (>80 mL).
Main Methods:
- Systematic literature search across PubMed, Scopus, and EBSCOhost up to June 2026.
- Inclusion of studies with validated measures for erectile function (IIEF) and ejaculatory function (MSHQ-EjD).
- Quality assessment using Newcastle-Ottawa Scale for cohorts and Cochrane RoB 2 tool for RCTs.
Main Results:
- Thirty studies (4635 patients) showed Rezūm generally preserves erectile and ejaculatory function across various prostate sizes.
- Significant relief of LUTS was observed, comparable to standard-sized glands even in prostates >80 mL.
- Low rates of severe adverse events (<1%); however, evidence quality was limited with high risk of bias in RCTs.
Conclusions:
- Rezūm WVTT appears to preserve sexual function while effectively managing urinary symptoms in BPH patients, including those with large prostates.
- The findings suggest a favorable sexual function profile compared to resective BPH treatments.
- Further high-quality research is needed to confirm these findings due to current evidence limitations.
