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Updated: Aug 6, 2026

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
Published on: October 22, 2019
18F-Fluorodeoxyglucose PET, the Brain, and Other Organs: From the First Human Studies (1976) to 2026
Abass Alavi1, Mona-Elisabeth Revheim2, Andrew B Newberg3
1Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Abstract:
The introduction of 18F-fluorodeoxyglucose (FDG) to medicine has been revolutionary during the past 5 decades, and its impact rivals that of other technical advances that have been made in medicine during the past century. Therefore, it is timely to celebrate the impact of this unique tracer and its critical role in so many domains of medicine, including the assessment and management of many serious diseases and disorders in the brain but also the entire body. FDG has lived up to the title molecule of the century. With the invention of total body PET instruments, the future looks just as promising.
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