Identifying candidate genes for trichome traits in grapevine through a genome-wide association study
Zhongyi Yang1, Yuxuan Zhou2, Lingling Hu2
1Zhejiang Wanli University, Ningbo, 315000, China. zyyang9266@zwu.edu.cn.
BMC Genomics
|July 21, 2026
Summary
This study identifies key genes controlling grape leaf trichome density using genome-wide association studies. These findings aid in breeding grapevines with enhanced resistance to pests and environmental stresses.
Area of Science:
- Plant Biology
- Genetics
- Agricultural Science
Background:
- Leaf trichomes are vital for plant photosynthesis and defense against stresses.
- Trichome distribution is a key trait for grape cultivar identification but its genetic basis is unclear.
Purpose of the Study:
- To conduct the first genome-wide association study (GWAS) on leaf trichome traits in grapevine.
- To identify genetic factors regulating trichome density and formation in grape leaves.
Main Methods:
- Genome-wide association study (GWAS) using resequencing data from 153 grape accessions.
- Two-year phenotypic observations of seven leaf trichome-related traits.
- Identification and functional enrichment analysis of candidate genes.
Main Results:
- Identified 201 significant single nucleotide polymorphisms (SNPs) and 314 candidate genes associated with trichome traits.
- Candidate genes are involved in transcriptional regulation, ubiquitination, signal transduction, and cell wall metabolism.
- Discovered a potential link between trichome density and stilbene synthase genes for chemical defense.
Conclusions:
- Provides novel insights into the genetic regulation of grapevine leaf trichome formation.
- Offers valuable genetic resources for breeding stress-resistant grape cultivars.
- Highlights potential for marker-assisted selection to improve grapevine resilience.
