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Related Experiment Videos

"Empty" sella: review of 76 cases.

K A Jaffer, E A Obbens, T A El Gammal

    Southern Medical Journal
    |March 1, 1979
    PubMed
    Summary

    Headache and symptoms of increased intracranial pressure are common in empty sella syndrome. Elevated cerebrospinal fluid (CSF) pressure in many patients suggests its role in the condition's development.

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    Area of Science:

    • Neurology
    • Endocrinology

    Background:

    • Empty sella syndrome is a condition where the sella turcica is partially or completely filled with cerebrospinal fluid.
    • Clinical presentation can be varied, often including headaches and signs of pituitary dysfunction.

    Purpose of the Study:

    • To investigate the clinical characteristics and potential pathogenetic factors of empty sella syndrome.
    • To assess the role of increased intracranial pressure in empty sella syndrome.

    Main Methods:

    • Retrospective review of 76 patient cases diagnosed with empty sella syndrome.
    • Analysis of presenting symptoms, including headache and signs of pituitary dysfunction.
    • Evaluation of cerebrospinal fluid (CSF) pressure in patients who underwent lumbar puncture.

    Main Results:

    • Headache was the primary complaint in 62% of cases.
    • 60% of patients exhibited symptoms related to increased intracranial pressure or pituitary dysfunction.
    • Elevated CSF pressure was observed in 56% (35 of 62) of patients who had lumbar puncture.

    Conclusions:

    • Increased intracranial pressure may be a significant factor in the pathogenesis of empty sella syndrome.
    • Clinical management should consider symptoms of elevated intracranial pressure and potential pituitary dysfunction.

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