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Amorphous selenium nanoparticles: synthesis strategies and multifunctional applications
Pratibha Chahal1, Avinash Singh1
1Department of Chemistry, SRM University Delhi-NCR Sonepat Haryana 131029 India singhavi06@gmail.com.
RSC Advances
|July 22, 2026
Summary
Amorphous selenium nanoparticles (a-SeNPs) offer enhanced biocompatibility and functionality over crystalline forms. This review explores their synthesis and diverse applications, from medicine to agriculture.
Area of Science:
- Nanotechnology
- Materials Science
- Biochemistry
Background:
- Selenium is an essential trace element for biological functions.
- Amorphous selenium nanoparticles (a-SeNPs) exhibit superior biocompatibility and reduced toxicity compared to crystalline selenium.
- The unique properties of a-SeNPs drive interest in their diverse applications.
Purpose of the Study:
- To review various synthesis strategies for amorphous selenium nanoparticles (a-SeNPs).
- To highlight the multifunctional applications of a-SeNPs.
- To discuss future perspectives in the field of a-SeNPs.
Main Methods:
- Exploration of chemical, hydrothermal, microwave-assisted, and biological synthesis routes for a-SeNPs.
- Analysis of the impact of size, shape, and amorphous nature on a-SeNP properties.
- Compilation of current research on a-SeNP applications.
Main Results:
- Biological synthesis yields a-SeNPs with enhanced stability and biocompatibility.
- a-SeNP properties are significantly influenced by their physical characteristics (size, shape, amorphous nature).
- a-SeNPs demonstrate potential in antioxidant, antibacterial, anticancer, bioimaging, biosensing, agricultural, and photocatalytic applications.
Conclusions:
- a-SeNPs represent a promising nanomaterial due to their advantageous properties.
- Diverse synthesis methods allow for tailored a-SeNP characteristics.
- a-SeNPs hold significant potential for various biomedical, agricultural, and environmental applications.
