Related Experiment Video
Updated: Aug 6, 2026

04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
The Case for N-acetylcysteine in Dengue Associated Liver Injury: Time for Definitive Evidence
Angela McBride1, Nguyen Lam Vuong2,3, Sudeep Adhikari4
1Pandemic Sciences Institute, University of Oxford, Oxford, UK.
Open Forum Infectious Diseases
|July 22, 2026
Abstract:
Dengue-associated liver injury is common, prognostically significant, and associated with high mortality at severe thresholds. Oxidative stress is a key, potentially modifiable mechanism. N-acetylcysteine has strong biological plausibility and supportive preclinical data, but clinical evidence remains limited, underscoring the need for well-designed randomized trials to inform practice and policy.
