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Updated: Aug 6, 2026
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Recording Horizontal Saccade Performances Accurately in Neurological Patients Using Electro-oculogram
Published on: March 13, 2018
Development of a transformation model to analyze horizontal saccadic velocity using electrooculography: a pilot
Da Young Kim1, Tae-Joon Kim1,2,3, Yunsoo Kim1
1Department of Neurology, Ajou University Hospital, Suwon, Republic of Korea.
Frontiers in Neuroscience
|July 22, 2026
Summary
Electrooculography (EOG) can now accurately measure saccadic eye movements, providing a practical alternative to expensive video-oculography (VOG). This study developed a transformation model to convert EOG signals into VOG-equivalent values for clinical use.
Area of Science:
- Neuroscience
- Ophthalmology
- Biomedical Engineering
Background:
- Saccadic eye movements are crucial biomarkers in neuroscience and neurology.
- Video-oculography (VOG) is the gold standard but is costly and lacks portability.
- Electrooculography (EOG) offers a practical alternative, but quantitative conversion to VOG values is needed.
Purpose of the Study:
- Develop and validate a mathematical model to estimate VOG-equivalent horizontal saccadic velocities from EOG recordings.
- Establish a reliable method for quantitative saccadic analysis using EOG.
Main Methods:
- Simultaneous EOG and VOG recordings in four healthy adults during horizontal gaze shifts.
- Derived an analytical relationship between EOG voltage velocity and angular eye velocity using a current-source model.
- Evaluated multiple high-pass filter settings and used leave-one-subject-out (LOSO) analysis for validation.
Main Results:
- A linear relationship was predicted and observed between EOG- and VOG-derived saccadic velocities.
- Optimal filtering (0.3 Hz high-pass, 35 Hz low-pass) yielded a transformation model with a common slope (0.146 °/μV) and direction-specific intercept.
- Converted EOG velocities showed no significant difference from VOG velocities, with stable LOSO validation coefficients.
Conclusions:
- A biophysically derived and validated EOG-to-VOG transformation model enables accurate horizontal saccadic velocity estimation.
- This model supports the feasibility of quantitative saccadic analysis using EOG as a practical alternative to VOG.
