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Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis
Published on: January 9, 2026
Case Report: Non-bacterial thrombotic endocarditis and multiple thrombi uncover a hidden prothrombotic mutation
Yongchao Luo1, Lanlin Zhang2, Xiang Zhang3
1Department of Breast Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Frontiers in Cardiovascular Medicine
|July 22, 2026
Summary
Non-bacterial thrombotic endocarditis (NBTE) in a teen was linked to a rare F2 gene mutation causing hereditary thrombophilia. Early diagnosis and treatment, including surgery and anticoagulation, led to full recovery and vein recanalization.
Area of Science:
- Cardiology
- Genetics
- Hematology
Background:
- Non-bacterial thrombotic endocarditis (NBTE) is a rare condition often linked to hypercoagulable states.
- Diagnosis can be difficult due to nonspecific symptoms and unclear etiology.
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