Related Experiment Video
Updated: Aug 6, 2026

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest
Published on: May 26, 2023
Intra- and Peri-Operative Cardiac Arrest in Pediatric Patients: Epidemiology, Risk Factors, Mechanisms, and
Eleni Asimacopoulos1, Gloria M Al Karaki1, Kirsten C Odegard1
1Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Pediatric intraoperative (IOCA) and perioperative cardiac arrest (POCA) remains a rare but serious event. Prevention focuses on risk assessment and preparedness, while management involves prompt resuscitation and considering extracorporeal cardiopulmonary resuscitation (ECPR).
Area of Science:
- Pediatric Anesthesiology
- Critical Care Medicine
- Cardiovascular Surgery
Background:
- Intraoperative (IOCA) and perioperative cardiac arrest (POCA) in pediatric patients is a rare but severe complication.
- Despite advancements, the incidence of IOCA/POCA in children has remained stable over 20 years, with rates of 3-22 per 10,000 noncardiac surgery cases.
Purpose of the Study:
- To review the epidemiology, risk factors, and mechanisms of pediatric IOCA and POCA.
- To provide clinicians with evidence-based management strategies for these critical events.
Main Methods:
- Systematic review of current evidence on pediatric IOCA and POCA.
- Synthesis of data on incidence, risk factors, and outcomes.
Main Results:
- Key risk factors include young age (neonates/infants), high ASA status, emergency surgery, congenital heart disease (CHD), and pulmonary hypertension.
- Respiratory events are the primary cause of anesthesia-related arrest; cardiovascular causes have higher mortality.
- Prevention strategies include preoperative risk stratification and team communication.
Conclusions:
- Effective management necessitates rapid recognition, high-quality cardiopulmonary resuscitation, and consideration of extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cases.
- Continued focus on prevention and preparedness is crucial for improving outcomes in pediatric cardiac arrest during surgery.
Related Concept Videos
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiopulmonary Resuscitation III: AED Use
Cardiopulmonary Resuscitation I: Adult
Introduction Cardiac Emergencies
Cardiopulmonary Resuscitation II: ACLS Airway Management

