A AIE Probe for Visual Monitoring of Endogenous and Exogenous H₂S and Food Freshness

Hydrogen sulfide (H₂S) is a crucial endogenous gas transmitter for the evaluation of food spoilage and disease diagnosis. Thus, we have effectively prepared a novel Aggregation-Induced Emission (AIE) probe EHAT, which displayed a obvious fluorescence color change after the addition of H₂S (from orangered to green), suggesting that probe EHAT can identify H₂S with the naked eye and the detection limit was calculated to be 1.5 × 10^-7 M for H₂S. The probe EHAT-based test strip was also developed to conveniently detect H₂S gas generated during food spoilage. Moreover, the probe EHAT were successfully utilized to image endogenous and exogenous H₂S in live cells.