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Updated: Aug 6, 2026

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
10:25

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Published on: June 5, 2021

Complement augments antibody neutralization of SARS-CoV-2 variants

Martin Jungbauer-Groznica1,2, Pierre Rosenbaum3, Isabelle Staropoli2

  • 1Antiviral Activities of Antibodies Group, Institut Pasteur, Université Paris Cité, Paris, France.

Science Translational Medicine
|July 22, 2026
PubMed
Summary

The complement system significantly boosts antibody effectiveness against SARS-CoV-2 variants like JN.1. This immune cooperation enhances neutralization, particularly for variants that evade antibodies, aiding in host defense against severe COVID-19.

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