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Published on: May 23, 2025

Web-based education and maternal awareness of Helicobacter Pylori infection in children with immune thrombocytopenia

Faten Mabrouk Nouh1, Hasan Abualruz2, Khaldoon Obiedate2

  • 1Lecturer of Pediatric Nursing, Faculty of Nursing, Menoufia University, Menoufia, Egypt; Faculty of Nursing, Al- Zaytoonah University of Jordan (ZUJ), Amman, Jordan.

Journal of Pediatric Nursing
|July 22, 2026
PubMed

Insights

A web-based education program significantly improved mothers' knowledge, practices, and attitudes concerning Helicobacter pylori infection in children with immune thrombocytopenia (ITP). This intervention offers a promising approach to enhance caregiver understanding and management of ITP-related H. pylori infections.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Health Education

Background:

  • Immune thrombocytopenia (ITP) is an autoimmune disorder causing low platelet counts.
  • Helicobacter pylori infection is linked to chronic ITP, with eradication potentially improving platelet levels.
  • Mothers are key in infection prevention and disease management for children with ITP.

Purpose of the Study:

  • To assess the impact of a web-based educational intervention.
  • To evaluate changes in mothers' knowledge, practices, and attitudes regarding H. pylori infection in children with ITP.

Main Methods:

  • A quasi-experimental study with a pretest-posttest design and a control group.
  • 100 mothers of children with ITP were divided into study (n=50) and control (n=50) groups.
  • Data collected via knowledge, self-reported practice, and attitude questionnaires.

Main Results:

  • The study group showed significant improvements in knowledge, practice, and attitude scores compared to the control group (p < .001).
  • ANCOVA confirmed significant intervention effects on knowledge (F=75.91) and attitude (F=306.45) scores (p < .001).
  • Positive correlations found between knowledge, practices, and attitudes (r=0.346 to 0.491, p < .001).

Conclusions:

  • A web-based educational program effectively enhanced mothers' understanding and management of H. pylori infection in children with ITP.
  • The findings support the use of digital health education to improve caregiver outcomes in pediatric hematological disorders.
Abstract

Keywords:
ChildrenHelicobacter pyloriImmune thrombocytopeniaMaternal awarenessWeb-based education

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