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Bioactive components in preterm and term human milk compared to donor human milk: A pilot study

Charlotte Høyer Rosenbæk1, Pingping Jiang2, Sofie Dahl-Nielsen3

  • 1Hans Christian Andersen's Children's Hospital, Odense University Hospital, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Denmark; Research Center GAIN (Gastrointestinal Diseases and Malformations in Infancy and Childhood), Odense University Hospital, Denmark; OPEN (Open Patient Data Explorative Network), Odense University Hospital, Region of Southern Denmark, Denmark.

Clinical Nutrition ESPEN
|July 22, 2026
PubMed
Summary

Mother's own milk (MOM) from preterm and term mothers is comparable in bioactive components. Donor human milk (DHM) has lower levels of milk fat globule membrane (MFGM) and associated proteins, suggesting reduced bioactive potential for preterm infants.

Keywords:
Donor human milkExtracellular vesiclesMilk fat globule membraneMother's own milkPretermTerm

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