Perihilar Cholangiocarcinoma in Primary Sclerosing Cholangitis
Asim Abdulhamid1, Gregory J Gores1, Julie K Heimbach2
1Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
None:
This clinical review details the current approach for the detection and management of perihilar cholangiocarcinoma in patients with primary sclerosing cholangitis. It summarizes the contemporary understanding of epidemiology, risk factors, current diagnostic tools and their limitations, and highlights emerging biomarkers currently under investigation. This review also discusses the role of neoadjuvant chemoradiation followed by liver transplantation as a potentially curative treatment.
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