Related Experiment Video

Updated: Aug 6, 2026

Revealing the Ferroptotic Phenotype of Medulloblastoma
04:01

Revealing the Ferroptotic Phenotype of Medulloblastoma

Published on: March 15, 2024

PLA2G2F suppresses ferroptosis through phospholipid remodeling

Yingying Hu1,2, Joleen Csuka3, Presha Rajbhandari4

  • 1Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature Structural & Molecular Biology
|July 22, 2026
PubMed
Summary

Researchers identified phospholipase A2 group IIF (PLA2G2F) as a key suppressor of ferroptosis in bladder cancer. This finding suggests that targeting PLA2G2F or its regulator, PPARG, could enhance cancer therapy.

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