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Updated: Aug 6, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Remote Assessment of Mobility in People with Parkinson's Disease: A Feasibility, Safety, Validity, Agreement, and
Carla Silva-Batista1, Kathleen T Scanlan1, Margaret E Stojak1
1Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA.
Background:
Mobility impairments are a hallmark of Parkinson's disease (PD). Telerehabilitation is becoming more common for people with PD; however, the validity and agreement of telerehabilitation's mobility measurements for people with PD are lacking.
Objectives:
We investigated the feasibility, safety, concurrent validity, agreement, and inter-rater reliability between remote and in-person home mobility assessments in people with PD.
Methods:
Sixty-two people with mild-to-moderate PD were assessed ON medication on two different days. On the first day, Rater A conducted home-based in-person mobility assessments that included the Five-Time Sit-to-Stand (5TSTS), Timed-Up-and-Go Test (TUG), and 360-degree Rapid-Turns Test (360°RTT). On the second day, Rater B conducted the same home-based mobility assessments remotely (via videoconferencing). Feasibility and safety were monitored. The concurrent validity and agreement between the remote and in-person mobility assessments were analyzed using the Pearson correlation coefficient and the Bland-Altman analysis, respectively. Inter-rater reliability was analyzed using the intraclass correlation coefficient (ICC).
Results:
Remote assessments were feasible and safe for all participants. Remote and in-person home mobility assessments, including 5TSTS (r = 0.95, P < 0.0001), TUG (r = 0.91, P < 0.0001), and 360°RTT for the dominant (r = 0.76, P < 0.0001) and non-dominant side (r = 0.77, P < 0.0001), were strongly and significantly correlated. Bland-Altman results showed relatively symmetrical distributions within the limits of agreement for all measurements. Inter-rater reliability was excellent (ICC ≥0.75) for all assessments.
Conclusions:
Home-based remote mobility assessments demonstrated feasibility, safety, validity, agreement, and excellent inter-rater reliability comparable to in-person assessments. Home-based, remote mobility assessments are comparable to in-person home mobility assessments in mild-to-moderate PD and can be implemented into telerehabilitation.

