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Hidden Neuroanatomy in the Sistine Chapel: Did Michelangelo Encode a Brain, or Do We Construct It?

Katerina Poprelka1, Maria Stefanatou1, Stylianos Gatzonis1

  • 1First Department of Neurosurgery, Evangelismos Hospital, National & Kapodistrian University of Athens, Athens, Greece.

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
|July 23, 2026
PubMed
Summary

Michelangelo's "Creation of Adam" may appear to depict a brain due to observer pareidolia, not intentional artistic design. This study integrates semiotics and neuropsychology to explore art interpretation.

Keywords:
Michelangeloartbrainneuropsychologysemiotics

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