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Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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Spatial biology in cancer epigenetics

Eva Crespo-García1, Manel Esteller1,2,3,4

  • 1Cancer Epigenetics Group, Sant Pau Research Institute (IRSantPau), Barcelona, Catalonia, Spain.

Molecular Oncology
|July 23, 2026
PubMed
Summary

Spatial epigenomics reveals gene regulation within intact tissues, overcoming limitations of bulk and single-cell sequencing. This powerful approach analyzes chromatin accessibility and modifications, offering new insights into cancer biology.

Keywords:
DNA methylationcancerchromatinepigeneticshistone modificationsspatial biology

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X-chromosome...
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