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Case Report: Intravitreal Aflibercept for Refractory Irvine-Gass Syndrome
Muataz Guma1, Jose Vargas1, Bader Alqahtani1
1Ophthalmology Division, King Abdullah University Hospital, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Introduction:
Irvine-Gass syndrome (pseudophakic cystoid macular edema) is a common postoperative complication of cataract surgery. While most cases resolve with topical therapy, refractory cases pose a therapeutic challenge.
Case Presentation:
A 60-year-old woman developed bilateral cystoid macular edema several weeks after uneventful phacoemulsification. Initial postoperative visual acuity was 20/20 bilaterally, declining to 20/100 despite topical corticosteroids and NSAIDs. Optical coherence tomography confirmed significant intraretinal cystic changes.
Intervention:
Bilateral intravitreal aflibercept (2.0 mg/0.05 mL) was administered.
Outcome:
Two weeks post-injection, optical coherence tomography demonstrated complete resolution of edema with restoration of best-corrected visual acuity to 20/20.
Conclusion:
Intravitreal aflibercept may be an effective treatment option for refractory Irvine-Gass syndrome.
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