Related Experiment Video For endometrial carcinoma
Updated: Aug 6, 2026

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
Published on: November 22, 2019
Ureteral Metastasis From Endometrial Carcinoma Mimicking Upper Tract Urothelial Carcinoma
Masataka Kubo1, Kazuhiro Takahashi1, Hiroaki Arakawa1
1Department of Urology The Jikei University School of Medicine, Kashiwa Hospital Chiba Japan.
Introduction:
Ureteral metastasis from endometrial carcinoma is extremely rare. We report a case identified at the time of the initial diagnosis of endometrial carcinoma.
Case Presentation:
A 64-year-old woman presented with suspected endometrial carcinoma. Contrast-enhanced computed tomography revealed hydronephrosis and a left ureteral mass suggestive of upper tract urothelial carcinoma (UTUC). Urine cytology showed malignant cells, but ureteroscopy was inconclusive. Because UTUC can affect management and prognosis, simultaneous surgery, including nephroureterectomy, was performed. Histopathological examination revealed ureteral adenocarcinoma morphologically similar to endometrial carcinoma. Immunohistochemical staining demonstrated PAX8 positivity, supporting the diagnosis of metastatic endometrial carcinoma. The final diagnosis was stage IVB endometrial carcinoma.
Conclusion:
Ureteral metastasis from endometrial carcinoma is extremely uncommon and may closely mimic UTUC on imaging, making preoperative diagnosis difficult.
Related Concept Videos
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection I: Introduction
Urinary Tract Calculi VI: Surgical Management
Ureters
Urinary Tract Calculi V: Nursing Management
