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Cranial Bone Density and Scalp Perfusion in Positional Plagiocephaly: Quantitative Assessment Using Low-Dose Computed
Taketoshi Yoshida1, Yasuhiro Kawahara2, Takaaki Oyama1
1Division of Neonatology, Maternal and Perinatal Center, Toyama University Hospital.
The Journal of Craniofacial Surgery
|July 23, 2026
Summary
Positional plagiocephaly in infants is linked to lower cranial bone density and scalp blood flow. Helmet therapy can significantly improve these metrics, suggesting reversibility with treatment.
Area of Science:
- Pediatric Radiology
- Cranial Deformities
- Infant Health
Background:
- Positional plagiocephaly is a common infant condition.
- Quantitative assessment of cranial bone characteristics is limited.
- Understanding bone density and perfusion is crucial for treatment evaluation.
Purpose of the Study:
- To assess cranial bone density and scalp perfusion in infants with positional plagiocephaly.
- To evaluate changes following helmet therapy using low-dose computed tomography (CT).
- To establish low-dose CT as a diagnostic tool for infant cranial deformities.
Main Methods:
- Retrospective analysis of 61 infants with moderate to severe positional plagiocephaly.
- Quantification of cranial bone density using Hounsfield units.
- Evaluation of scalp perfusion and changes post-helmet therapy in 10 infants.
Main Results:
- Infants with positional plagiocephaly showed significantly lower bone density on the flattened side (P<0.001).
- Reduced scalp perfusion was observed on the flattened side (P<0.01).
- Helmet therapy led to significant improvements in both bone density and scalp perfusion.
Conclusions:
- Positional plagiocephaly is associated with localized reductions in bone density and perfusion.
- These deficits appear reversible with appropriate helmet therapy.
- Low-dose CT is a practical tool for diagnosing and quantifying infant cranial deformities.

