[Impact of a 3-Month Ketogenic Diet on Euthymia in Bipolar II Disorder: A Case Report]

Metabolic theories of various psychiatric disorders are generating growing interest within the medical community. These theories are supported by an emerging scientific literature suggesting a central role of neuronal energy dysfunction in diverse psychopathologies. In parallel, the use of metabolic interventions is gaining credibility in the management of psychiatric disorders such as bipolar disorder. We present here the case of a 34-year-old woman with a known diagnosis of bipolar disorder type II, mixed personality disorder, and alcohol and cannabis use disorder, who exhibits euthymia with persistent residual anxio-depressive symptoms and impaired overall functioning. As part of a therapeutic approach complementary to psychopharmacology, the patient undertook a ketogenic nutritional intervention lasting 3 months. At the end of the intervention, a clinically significant improvement was observed, both in anthropometric parameters and in psychiatric symptoms. The patient also reported a marked improvement in her level of daily functioning and quality of life. This case contributes to the growing body of literature supporting the potential of metabolic interventions in psychiatry and highlights the relevance of pursuing systematic exploration of these approaches in the treatment of mood disorders.