Aggressive Primary Sacral Non-Hodgkin Lymphoma Associated With Systemic Lupus Erythematosus
Claudia Katiuska Gonzalez-Valdez1, Gabriel Galvan-Salazar2, Sharon Herrera-Cifuentes3
1Neurosurgery and Radiosurgery Department, Oncology Centre, Hospital Espanol, Mexico City, Mexico.
Journal of Medical Cases
|July 23, 2026
Summary
A rare, aggressive sacral non-Hodgkin lymphoma case is presented in a 36-year-old female with systemic lupus erythematosus. Despite treatment, the diffuse large B-cell lymphoma showed rapid progression and widespread metastasis, leading to a poor prognosis.
Area of Science:
- Oncology
- Hematology
- Radiology
Background:
- Sacral non-Hodgkin lymphoma is a rare bone pathology, accounting for 1-7% of spinal tumors.
- The co-occurrence of sacral lymphoma with systemic lupus erythematosus is uncommon and associated with aggressive disease.
- This case report details a 36-year-old female with these rare conditions.
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