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A Delicate Balance: Immunotherapy for Endometrial Cancer in a Patient With Multiple Sclerosis
Antonio Ruggiero1,2,3, Chiara Redemagni4,3, Cristina Angela Camnasio1,2
1Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Journal of Medical Cases
|July 23, 2026
Summary
Immune checkpoint inhibitors (ICIs) show potential safety in select advanced endometrial cancer patients with stable multiple sclerosis (MS). Careful patient selection and monitoring are key for managing MS during cancer treatment.
Area of Science:
- Oncology
- Neurology
- Immunology
Background:
- Multiple sclerosis (MS) is a chronic immune-mediated condition.
- Immune checkpoint inhibitors (ICIs) are crucial in cancer therapy but their use in MS patients is under-researched.
- Limited data exists on ICI safety in older patients and first-line endometrial cancer (EC) treatment.