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Successful Treatment of Granuloma Faciale With Deep Dermal Inflammatory Infiltration Using Intralesional
Mioka Homma1, Tatsuya Katsumi1, Ryoya Ohashi1
1Department of Dermatology, Faculty of Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, JPN.
Abstract:
A 46-year-old man presented with asymptomatic dark reddish nodules on the left nasal ala and lower jaw, including a 1-cm nodule on the nasal ala. Histopathological examination revealed diverse inflammatory cell infiltration extending into the deep dermis and the presence of a grenz zone. Based on these findings, he was diagnosed with granuloma faciale (GF). Intralesional corticosteroid injections were selected because of their strong anti-inflammatory effects and efficacy in treating deep dermal lesions. Although various treatment modalities have been attempted, GF is often refractory to treatment. In this case, the lesion resolved completely after three intralesional corticosteroid injections.