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Updated: Aug 6, 2026

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Virtual Agent for Real-Time Motivational Interviewing by Integrating Adaptive Nonverbal Behavior and Language Models
Published on: December 23, 2025
Can Motivational Interviewing be delivered using Artificial Intelligence chatbots? Evaluating the capability of
Candice Oster1, Richard Leibbrandt2, Judith Hocking1
1Flinders University, College of Nursing & Health Sciences, Caring Futures Institute, Adelaide, Australia.
Patient Education and Counseling
|July 23, 2026
Summary
Generative Pre-Trained Transformer (GPT-4o) shows promise in delivering Motivational Interviewing (MI) behaviors but needs improvement for proficiency. Further research is essential to enhance AI capabilities for accessible and cost-effective MI delivery.
Area of Science:
- Artificial Intelligence in Healthcare
- Behavioral Science
- Digital Health Interventions
Background:
- Motivational Interviewing (MI) is a patient-centered counseling approach to facilitate behavior change.
- Large Language Models (LLMs) offer potential for scalable digital health solutions.
- Evaluating AI's capability in delivering complex therapeutic techniques like MI is crucial.
Purpose of the Study:
- To systematically assess the proficiency of Generative Pre-Trained Transformer (GPT-4o) in delivering Motivational Interviewing.
- To analyze GPT-4o's adherence to MI principles and identify patterns in its conversational responses.
- To determine the potential of AI in enhancing accessibility and reducing costs of MI delivery.
Main Methods:
- OpenAI's GPT-4o was prompted to conduct simulated Motivational Interviews with patient actors.
- Interview transcripts were analyzed using the Motivational Interviewing Treatment Integrity (MITI) code.
- Conversation sequences were examined for patterned responses related to MI behaviors.
Main Results:
- GPT-4o exceeded 'good' competency thresholds for specific MI behaviors like complex reflections and reflection-to-question ratio.
- High counts of MI-adherent behaviors were observed, with minimal non-adherent behaviors.
- GPT-4o scored below 'fair' competency for global relational and technical skills, showing a tendency to shift towards persuasion.
Conclusions:
- GPT-4o demonstrates a capacity to mimic MI behaviors but requires further development for proficient delivery.
- AI-driven MI holds potential for increased accessibility and reduced costs.
- Further research into AI augmentation techniques is necessary before widespread implementation of LLMs like GPT-4o for MI.
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