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Updated: Aug 6, 2026

MitoCeption: Transferring Isolated Human MSC Mitochondria to Glioblastoma Stem Cells
Published on: February 22, 2017
Mitochondrial transfer: quality dictates immune-metabolic fate
Kai Liu1, Quazi T H Shubhra2, Hui Zhang3
1College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
None:
Horizontal mitochondrial transfer (HMT) outcomes are shaped by donor fitness and transfer context. We propose a post-transfer quality checkpoint that integrates membrane potential, oxidative damage, mitophagy, fusion, and fission to determine the recipient-cell's response. Depending on donor quality and recipient thresholds, HMT may drive bioenergetic restoration, inflammation, or tumor immune escape. This framework extends route-centered accounts of HMT toward a testable, quality-governed model for therapeutic intervention.
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