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Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
The COMPLETE-CRC Screening Initiative: Increasing Colonoscopy Completion After Positive Stool-Based Colorectal Cancer
Akram Abushamma1, Susannah Wolfe2, Gabriella Lakatos2
1Department of Internal Medicine, Cleveland Clinic Akron General, Cleveland Clinic, Akron, OH, USA.
Patient navigator outreach improved colonoscopy completion after positive stool-based tests (SBTs) for colorectal cancer (CRC) screening. However, completion rates remain suboptimal, especially for older adults, highlighting the need for enhanced CRC screening strategies.
Area of Science:
- Colorectal Cancer Screening
- Public Health Interventions
- Quality Improvement in Healthcare
Background:
- Stool-based tests (SBTs) are increasingly utilized for colorectal cancer (CRC) screening.
- Suboptimal follow-up colonoscopy completion rates after positive SBT results present a significant challenge in CRC screening programs.
Purpose of the Study:
- To achieve a colonoscopy completion rate of ≥80% within six months of patient navigator contact for Ohio patients with positive SBTs.
- To identify factors influencing colonoscopy completion rates following positive SBT results.
Main Methods:
- A quality improvement study involving adults aged 45-75 with positive SBTs.
- Patient navigators contacted individuals who had not completed colonoscopy within 360 days via phone and/or MyChart.
- Colonoscopy completion within six months of navigator contact was the primary outcome; multivariable logistic regression analyzed associated factors.
Main Results:
- Of 2,548 patients with positive SBTs, 803 (31.5%) had not completed colonoscopy within 360 days.
- Patient outreach increased overall colonoscopy completion from 68.5% to 70.2%.
- Direct patient contact significantly improved completion rates (16.7% vs. 2.1% for indirect outreach; p<0.001), while older age was associated with lower completion (aOR 0.94; p=0.007).
Conclusions:
- Patient outreach initiatives positively impact colonoscopy completion following positive SBTs for CRC screening.
- Older age emerged as a significant factor associated with lower colonoscopy completion rates.
- Despite observed improvements, colonoscopy completion rates remain suboptimal, necessitating further optimization of CRC screening outreach strategies.
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