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New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Fulminant liver dysfunction after endovascular pharmacomechanical thrombectomy for peripheral arterial occlusive
Ho-Ching Leung1, Dexter Yak-Seng Chan1, Yiu Che Chan1
1Division of Vascular and Endovascular Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, SAR, China.
Abstract:
Derangement of liver function is a rare, but known, complication of percutaneous pharmacomechanical thrombectomy (PMT). PMT can cause intravascular hemolysis, which results in cell-mediated and direct hepatocellular toxicity. We report the case of a patient who suffered such a complication, and recovered with close monitoring of liver function in an intensive care setting. Further studies will elucidate the risk factors for and mechanisms of post-thrombectomy acute hepatitis, and providers should maintain a high index of suspicion in patients who have recently undergone PMT.
Insights
Percutaneous pharmacomechanical thrombectomy (PMT) can rarely cause liver damage through intravascular hemolysis. This case highlights the importance of monitoring liver function after PMT to manage potential acute hepatitis.
Area of Science:
- Hepatology
- Interventional Cardiology
- Nephrology
Background:
- Percutaneous pharmacomechanical thrombectomy (PMT) is an established procedure for treating thromboembolic events.
- While effective, PMT carries rare but significant complications, including liver injury.
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