Related Experiment Video
Updated: Aug 6, 2026

07:55
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Is FAP the key to unlocking treatment for rare soft-tissue sarcomas?
1Department of Radiology and Imaging Sciences, Emory University Atlanta, Georgia 30322, United States.
Summary
Fibroblast activation protein (FAP) is a promising target for solitary fibrous tumors (SFTs). 90Y-FAPI-46 shows therapeutic potential in FAP-expressing SFTs, offering a new treatment option.
Area of Science:
- Oncology
- Radiopharmaceuticals
- Molecular Imaging
Background:
- Fibroblast activation protein (FAP) is significantly overexpressed in several sarcoma types, including solitary fibrous tumors (SFTs).
- FAPI tracers are emerging as valuable tools for both diagnosis and therapy in oncology.
- FAP expression levels can vary, necessitating biomarkers for targeted treatment selection.
![Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F68356.jpg&w=3840&q=50)
![An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F66708.jpg&w=3840&q=50)