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Updated: Aug 6, 2026

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Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Influence of Traumatic Brain Injury on Bone Healing Rate in Mandibular Fractures: A Prospective Comparative Study
Kannan Balaraman1, Vimal Kumar Kummari2, S Raja Sabapathy1
1Department of Plastic, Hand, Maxillofacial and Burns Surgery, Ganga Hospital, Coimbatore 641043, India.
Craniomaxillofacial Trauma & Reconstruction
|July 24, 2026
Summary
Traumatic brain injury (TBI) accelerates mandibular fracture healing, with callus formation occurring about 4.5 days sooner. High-frequency ultrasonography effectively monitors this accelerated bone healing without radiation.
Area of Science:
- Orthopedics
- Trauma Surgery
- Neurosurgery
Background:
- Accelerated bone healing in long bone fractures is known in traumatic brain injury (TBI) patients.
- Mandibular fracture healing in TBI patients is less understood.
- This study investigates mandibular fracture healing rates in TBI vs. non-TBI patients.
Purpose of the Study:
- To compare mandibular fracture healing rates in patients with and without TBI.
- To assess the efficacy of high-frequency ultrasonography in monitoring fracture healing.
Main Methods:
- Prospective comparative study of 77 patients with mandibular fractures (June 2020-Nov 2021).
- Patients divided into TBI (Group 1) and non-TBI (Group 2) groups.
- Fracture healing assessed weekly for 4 weeks using high-frequency ultrasonography (6-15 MHz) to evaluate callus formation.
Main Results:
- Mean time to initial callus formation was significantly shorter in TBI patients (15.45 days) vs. non-TBI patients (19.98 days).
- Soft callus was evident earlier in TBI patients (27.3% vs. 9.1% by week 2).
- Hard callus formed significantly earlier in TBI patients (72.7% vs. 27.3% by week 4).
Conclusions:
- Mandibular fractures heal faster in patients with TBI, with callus formation approximately 4.5 days earlier.
- High-frequency ultrasonography is an effective, radiation-free tool for serial fracture assessment.
- Findings can guide surgical timing and follow-up for polytrauma patients.

