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Updated: Aug 6, 2026
08:21
Forming Micro-and Nano-Plastics from Agricultural Plastic Films for Employment in Fundamental Research Studies
Published on: July 27, 2022
Micro- and Nanoplastics as Emerging Cardiovascular Risk Factors: A Systematic Review
Dominika Kaczyńska1, Emilia Malik1, Kamil Szemik1
1Students' Scientific Association of Computer Analysis and Artificial Intelligence, Department of Radiology and Nuclear Medicine, Medical University of Silesia, 40-055 Katowice, Poland.
Journal of Xenobiotics
|July 24, 2026
Summary
Micro- and nanoplastics (MNPs) are increasingly found in human blood and tissues. While studies suggest possible links to cardiovascular disease, more research is needed to confirm these associations.
Area of Science:
- Environmental Health
- Cardiovascular Science
- Toxicology
Background:
- Micro- and nanoplastics (MNPs) are pervasive environmental contaminants.
- Increasing detection of MNPs in human tissues and biological fluids raises health concerns.
- Evidence suggests MNPs may be linked to cardiovascular pathology.
Purpose of the Study:
- To systematically review and synthesize existing evidence on the association between MNPs and cardiovascular pathology.
- To evaluate the quality and certainty of evidence regarding MNPs and cardiovascular disease.
Main Methods:
- Systematic literature search (PubMed, Scopus, Web of Science, Embase) following PRISMA guidelines.
- Inclusion of original human studies from the last 10 years.
- Narrative synthesis due to methodological heterogeneity; risk of bias and certainty of evidence assessed (ROBINS-E, GRADE-informed).
Main Results:
- MNPs detected in various cardiovascular-related matrices.
- Possible associations suggested with major adverse cardiovascular events, acute coronary syndrome, myocardial infarction, arterial stenosis, vascular calcification, thromboembolic disease, hypertension, inflammatory markers, coagulation, and lipid profiles.
- Certainty of evidence was very low; most studies had high or very high risk of bias.
Conclusions:
- Current evidence indicates a potential association between MNPs and cardiovascular pathology.
- Causality remains unproven.
- Need for larger prospective studies with standardized protocols, contamination control, and confounder adjustment.
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