Posterior Single-Window Ultrasound-Guided Cryoneurolysis for Severe Pediatric Spastic Equinovarus: Technical
Luigi Di Lorenzo1,2, Hassan Zmerly2, Emiliano Agliaroro1
1Istituto Neurologico Mediterraneo Neuromed IRCCS, 86042 Pozzilli, Italy.
Insights
A new posterior single-window ultrasound-guided cryoneurolysis technique simplifies treatment for severe pediatric spastic equinovarus. This minimally invasive approach improved spasticity and caregiver satisfaction in a child with cerebral palsy.
Area of Science:
- Pediatric Orthopedics
- Neurology
- Minimally Invasive Procedures
Background:
- Severe pediatric spastic equinovarus significantly impacts mobility, hygiene, and daily care, particularly in children with cerebral palsy (CP).
- Existing treatments for spastic equinovarus in CP are often limited, with outcomes focusing on caregiver burden and daily function rather than gait restoration.
- Ultrasound-guided cryoneurolysis offers a minimally invasive option for spasticity, but its application in severe deformities presents technical challenges.
Abstract:
Background and Clinical Significance: Severe pediatric spastic equinovarus may significantly impair positioning, orthotic tolerance, hygiene management, caregiver-assisted mobilization, and assisted standing activities. In children with severe cerebral palsy, clinically meaningful outcomes frequently include reduction in caregiver burden and facilitation of daily care rather than restoration of autonomous gait. Ultrasound-guided cryoneurolysis has recently emerged as a minimally invasive option for focal spasticity management, although procedural workflow and tolerability remain challenging in severe deforming patterns. Case Presentation: We report a CARE-compliant same-patient bilateral technical comparison in a 9-year-old child with severe spastic cerebral palsy and bilateral dynamic equinovarus refractory to intensive rehabilitation and repeated botulinum toxin treatment. Baseline severity was consistent with GMFCS level IV. One lower limb was treated using the proposed posterior single-window ultrasound-guided cryoneurolysis approach through a single posterior proximal-calf window, whereas the contralateral limb underwent a conventional multi-point supine strategy. The posterior single-window approach enabled sequential targeting of multiple motor branches through a single posterior access corridor under continuous ultrasound guidance. The procedure required approximately 1 mL of 2% lidocaine without additional sedation and was completed in approximately 4 min, whereas the conventional supine strategy required multiple access points, repeated probe repositioning, minimal conscious sedation with midazolam, and approximately 20 min. At follow-up, lower-limb spasticity improved from approximately MAS 3 toward MAS 2, passive ankle angle, measured as the tibia-foot angle with 90° corresponding to the neutral ankle position, improved from approximately 80° to 95°, and semitendinosus-related hypertonia was reduced. Clinically meaningful improvement in positioning, hygiene management, assisted standing, and rehabilitation handling was observed. Caregiver-reported satisfaction and procedural tolerability were qualitatively perceived as better with the posterior single-window approach. Conclusions: The proposed posterior single-window cryoneurolysis strategy may represent a technically simplifying and clinically relevant minimally invasive approach for severe pediatric spastic equinovarus. Further prospective studies are required to confirm reproducibility, safety, and long-term outcomes.
