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Updated: Aug 6, 2026

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
[Migraine aura: differential diagnostics between ophthalmology and neurology]
Carl H Göbel1,2, Axel Heinze3, Katja Heinze-Kuhn3
1Schmerzklinik Kiel, Migräne- und Kopfschmerzzentrum, Heikendorfer Weg 9-27, 24149, Kiel, Deutschland. cg@schmerzklinik.de.
Die Ophthalmologie
|July 24, 2026
Summary
Migraine aura involves temporary neurological symptoms like visual disturbances. Recognizing its gradual onset and spread is key for diagnosis and distinguishing it from other conditions.
Area of Science:
- Neurology
- Neuroscience
Background:
- Migraine aura is a common phase of migraine, affecting 25-35% of patients.
- It involves fully reversible focal neurological symptoms, often visual, sensory, or motor.
- Symptoms typically develop gradually, spread over time, and occur in succession.
Purpose of the Study:
- To review the clinical spectrum of migraine aura based on ICHD-3 criteria.
- To emphasize the characteristic temporal evolution of aura symptoms.
- To highlight the recognition of isolated aura without headache and differential diagnosis.
Main Methods:
- Review of clinical spectrum of migraine aura.
- Application of International Classification of Headache Disorders, 3rd edition (ICHD-3) diagnostic criteria.
- Emphasis on temporal evolution and differential diagnosis.
Main Results:
- Migraine aura encompasses a range of neurological symptoms, most commonly visual.
- Key diagnostic features include gradual onset, progressive spread, and complete resolution within 5-60 minutes.
- Distinguishing migraine aura from transient ischemic attacks, epilepsy, and retinal disorders is crucial.
Conclusions:
- Understanding the ICHD-3 criteria and temporal evolution aids in diagnosing migraine aura.
- Recognition of isolated aura and differentiation from other neurological events are important clinical skills.
- Migraine aura simulations can aid in patient education and history-taking.
