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Treatment-Effect-Based Versus Risk-Based Targeting of Care Management Outreach in Medicaid: A Retrospective Cohort
Sanjay Basu1,2, Sadiq Y Patel2,3, Rajaie Batniji2
1Department of Medicine, University of California, San Francisco, California, USA.
Population Health Management
|July 24, 2026
Summary
Targeting Medicaid care management outreach by predicted treatment effect, not just risk, significantly improves acute event prevention. This approach is more effective and equitable for beneficiaries.
Area of Science:
- Health Services Research
- Causal Inference
- Health Economics
Background:
- Medicaid care management often targets high-risk beneficiaries for outreach.
- This strategy assumes risk and responsiveness are aligned and stable.
- Limited outreach capacity necessitates efficient targeting methods.
Purpose of the Study:
- To compare the effectiveness of targeting outreach by predicted individualized treatment effect (CATE) versus risk-based targeting.
- To evaluate if monthly re-estimation of CATE improves acute event prevention in Medicaid programs.
- To assess the impact of targeting strategies on acute events and disparities.
Main Methods:
- Analysis of 164,063 adult Medicaid beneficiaries in Washington and Virginia (Jan 2023-Dec 2025).
- Causal forest with cross-fitted nuisance functions and within-person fixed effects to estimate CATE.
- Comparison of risk-based vs. effect-based targeting rules at 10% capacity using off-policy evaluation.
Main Results:
- Effect-based targeting prevented 13.3 acute events per 2000 members/month, compared to 2.5 for risk-based targeting (a 5.3-fold improvement).
- Within-person variance explained 63.6% of the total CATE variance, highlighting individual responsiveness.
- Gains in event prevention were consistent across racial/ethnic groups and states.
Conclusions:
- Monthly allocation of Medicaid care-management outreach by predicted treatment effect significantly increases acute events prevented.
- This effect-based targeting strategy is more efficient than risk-based targeting at fixed capacity.
- The approach substantially improved outcomes without widening between-group disparities.