Neurodevelopmental Impact of Copy Number Variants in Patients With Treatment-Resistant Schizophrenia

Wenxin Bian1, Rose Mary Xavier2,3,4, Tyler E Dietterich5,6

  • 1School of Nursing, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Summary

Copy number variations (CNVs) are linked to neurodevelopmental disorders (NDDs) in individuals with treatment-resistant schizophrenia (TRS). CNV carriers showed a higher burden of NDDs, especially learning disabilities, compared to non-carriers.

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