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Successfully performed video capsule endoscopy in an 8-month-old infant weighing 7.5kg

Paul-Christoph Zeisler1, Robert Thimme1, Ulrike Teufel-Schaefer2

  • 1Department of Medicine II Medical Center - University of Freiburg Freiburg Baden-Württemberg Germany.

JPGN Reports
|July 25, 2026
PubMed

Insights

Video capsule endoscopy (VCE) successfully diagnosed small bowel bleeding in an 8-month-old infant. This case highlights VCE

Area of Science:

  • Pediatric Gastroenterology
  • Minimally Invasive Diagnostic Imaging

Background:

  • Video capsule endoscopy (VCE) is a standard diagnostic method for small bowel examination.
  • Data regarding VCE application in infants, particularly those with complex medical histories, remain limited.
  • Small bowel bleeding is a significant concern in infants post-allogeneic hematopoietic stem cell transplantation (HSCT).

Purpose of the Study:

  • To report the first detailed case of successful PillCam®SB3-VCE in a very young, low-weight infant.
  • To evaluate the feasibility and safety of VCE in diagnosing obscure gastrointestinal bleeding in infants.
  • To assess the utility of VCE in the context of post-HSCT complications.

Main Methods:

  • A PillCam®SB3 capsule was endoscopically inserted into the duodenum of an 8-month-old infant (7.5 kg) with suspected small bowel bleeding.
  • No bowel preparation or patency capsule testing was performed prior to capsule insertion.
  • The procedure was performed due to suspected small bowel bleeding following allogeneic HSCT.

Main Results:

  • Video capsule endoscopy successfully identified the source of bleeding in the terminal ileum and cecum.
  • The procedure was technically successful without immediate complications.
  • The findings guided subsequent clinical management.

Conclusions:

  • Video capsule endoscopy can be safely and effectively performed in very young, low-weight infants when clinically indicated for suspected small bowel bleeding.
  • Careful consideration of infant-specific anatomical and physiological factors is crucial for successful VCE application.
  • VCE represents a valuable tool for diagnosing obscure gastrointestinal bleeding in pediatric patients, including those with complex post-transplant conditions.

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