Related Experiment Video
Updated: Aug 5, 2026

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds
Published on: January 7, 2019
Dual-Scaffold Technique: Autologous Minced Cartilage and Bone Marrow Aspirate Scaffold Combined With Synthetic
Leonardo Ataíde1,2, Moises Cohen1,3, Pedro Debieux1,3
1Department of Orthopaedic Surgery Einstein Hospital Israelita São Paulo Brazil.
Abstract:
Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix-induced chondrogenesis plus procedure for full-thickness knee cartilage lesions uses a collagen matrix combined with shaver-minced cartilage graft and bone marrow aspirate. It merges a source of bone marrow-derived stem cells and a biological autologous cartilage scaffold, leveraging their chondrogenic differentiation capacity and paracrine activity. This technique aims to enhance outcomes and provides an associated single-stage knee cartilage repair option with biological augmentation.

