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Updated: Aug 5, 2026
Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
The Biologically Enhanced Anterior Cruciate Ligament Reconstruction With Combined Injection of Harvested
Akram Aldawoudy1, Micheal T Hirschmann2,3, Ahmed Abdalla Ahmed Abdelgawad1
1Alex Knee Center Alexandria Egypt.
Abstract:
Despite continuous advances, anterior cruciate ligament reconstruction still struggles to restore full native knee function, as most techniques improve mechanical stability but overlook biological healing. The described superenhanced anterior cruciate ligament reconstruction technique aims to address this biological problem through a quadruple approach. The native anterior cruciate ligament stump is preserved, autologous bone "biosticks" are used to enhance tunnel osteointegration, and incorporates platelet-rich plasma, and the bone marrow aspirate concentrate in a gel-like structure to boost graft revascularization.
