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Published on: March 18, 2020
Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery
Lin-Lin Lan1, Qiu-Rong Yang1,2, Pei-Yun Zhuang1
1Department of Voice Medicine, Xiamen Key Laboratory of Voice Medicine, Zhongshan Hospital of Xiamen University, School of Medicine Xiamen University Xiamen China.
Objective:
The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest duration using a controlled rabbit model.
Methods:
Building on our established rabbit model for graded voice rest, we created two distinct phonomicrosurgery injury models: one involving the superficial lamina propria (SLP) and another extending to the mid-deep lamina propria (MDLP). The effects of different voice rest durations on wound healing were systematically evaluated through ex vivo laryngeal phonatory vibration experiments, histopathological examinations (hematoxylin-eosin, Alcian Blue, and Elastica van Gieson staining), and Gray Level Co-occurrence Matrix texture analysis.
Results:
The optimal voice rest duration was dependent on surgical depth. In the SLP surgery model, a 1-day voice rest period resulted in the most favorable outcomes, characterized by superior voice quality and histological organization. In contrast, for the MDLP surgery model, a 3-day voice rest duration promoted optimal wound healing, yielding better vocal function, improved vibration, and reduced tissue fibrosis.
Conclusion:
Voice rest requirements differ based on surgical depth.
